Mark Scheme
1. A stimulus is a change in the environment (internal or external) detected by receptors [1]; a response is the reaction of an effector (muscle or gland) to a stimulus [1] [2]
2. Sensory neurone: carries impulses from receptor to the spinal cord/relay neurone; Relay neurone (interneurone): connects sensory and motor neurones in the spinal cord/brain; Motor neurone: carries impulses from relay neurone to the effector (muscle or gland) [6 — 2 per row]
3. A reflex arc bypasses the brain [1]; the impulse travels a shorter pathway (through the spinal cord only), so the response is faster [1] [2]
4. The impulse reaches the end of the pre-synaptic neurone [1]; neurotransmitter molecules are released into the synaptic gap [1]; they diffuse across and bind to receptors on the post-synaptic neurone, triggering a new impulse [1] [3]
5. Speed: nervous = fast; hormonal = slow; Duration: nervous = short-lived; hormonal = long-lasting; Transmission: nervous = electrical impulse along neurones; hormonal = chemical carried in blood [6 — 2 per row]
6. A hormone is a chemical messenger produced by a gland and transported in the blood to a target organ [1]; Insulin: pancreas; Glucagon: pancreas; Adrenaline: adrenal glands [4 — 1 for definition + 1 per correct gland]
7. Homeostasis is the maintenance of a stable internal environment [1]; negative feedback: when a condition moves away from the set point, a corrective response is triggered [1]; the response brings the condition back to normal, which then switches off the response [1] [3]
8. Blood glucose rises; the pancreas detects this [1]; pancreas releases insulin [1]; insulin causes liver (and muscle) cells to convert glucose to glycogen (glycogenesis) [1]; blood glucose falls back to normal [1] [4]
9. Blood glucose falls; the pancreas releases glucagon [1]; glucagon causes the liver to convert glycogen back to glucose (glycogenolysis) [1]; blood glucose rises back to normal [1] [3]
10. The hypothalamus [1]
11. Any three: sweating — water evaporates from skin surface, removing heat energy [2]; vasodilation — blood vessels near the skin surface widen, more blood flows to skin, more heat lost by radiation [2]; hairs lie flat — erector muscles relax, hairs are flat, less insulating air trapped [2] [6]
12. Any two: shivering — rapid muscle contractions generate heat [2]; vasoconstriction — blood vessels near the skin surface narrow, less blood flows to skin, less heat lost [2]; hairs stand on end — erector muscles contract, hairs trap an insulating layer of air [2] [4 — 2 per response]